Fig. 4.

Association of FADS genotypes with variations in n-3 LCPUFA levels (%). In each graph and for each SNP, the first bar represents the reference value [the mean level (±SD) of the n-3 LCPUFA in homozygotes for the major allele]. The second and third bars indicate the n-3 LCPUFA level in heterozygote and homozygotes for the minor allele, respectively, calculated as a percentage of the reference value. White and black bars represent heterozygotes and homozygotes, respectively. All tests were adjusted for age, gender, BMI, and center. Significant associations (P < 0.0003) are indicated by boxes around the SNP.