TABLE 2.

Lipid compositions and concentrations used in simulations

Lipid Compositionsa Determined by Lipidomics
	apoA-I	SM	PC	FCho	ChoE	TG	lysoPC
Normal HDL-C	2	18	109	50	90	19	10
Low HDL-C	2	13	109	25	81	24	5
High HDL-C	2	23	109	75	99	14	15

Average Concentrationsb of Lipid Classes Determined by Lipidomics
	SM	HDL-C	ChoE	TG	lysoPC
Low HDL-C	0.057 ± 0.003	7.545 ± 0.200	0.105 ± 0.009	0.436 ± 0.024	0.014 ± 0.007
High HDL-C	0.082 ± 0.004	10.928 ± 0.254	0.132 ± 0.020	0.244 ± 0.036	0.022 ± 0.002

Abbreviations: Apo, apolipoprotein; ChoE, cholesteryl ester; FCho, free cholesterol; HDL-C, high-density lipoprotein cholesterol; LDL-C, low-density lipoprotein cholesterol; lysoPC, lysophosphatidylcholine; SM, sphingomyelin; TG, triacylglycerol.

^aNumber of molecules per HDL particle.

^bUnits are μmol/l [lipid] / mg/dl [apoA-I].