. 2010 Aug;51(8):2405–2412. doi: 10.1194/jlr.P900015

TABLE 2.

Mean percent changes (± SD) of variables of 19 severely obese women following gastric bypass surgery compared with baseline values

Variable	1 Month	3 Month	6 Month	12 Month
BMI	−10 ± 2^a	−18 ± 4^ab	−25 ± 5^abc	−32 ± 6^bcd
Fat mass	−12 ± 3^a	NA	NA	−51 ± 11^ab
Lean mass	−10 ± 4^a	NA	NA	−16 ± 13^ab
Waist/hip ratio	−5 ± 9	−6 ± 7^a	−7 ± 9^ab	−6 ± 9^a
Glucose	−7 ± 12	−10 ± 12^a	−13 ± 12^ab	−14 ± 14^ab
Insulin	−36 ± 37^a	−49 ± 20^ab	−57 ± 17^ab	−59 ± 18^ab
HOMA-IR	−38 ± 42^a	−53 ± 22^a	−62 ± 18^ab	−63 ± 18^ab
Total-C	−10 ± 24	−3 ± 26	−4 ± 23	−7 ± 15
LDL-C	−8 ± 31	−4 ± 30	−6 ± 28	−15 ± 19
HDL-C	−16 ± 24^a	−2 ± 20^b	8 ± 20^bc	15 ± 20^abcd
LDL/HDL	12 ± 29	−11 ± 15^b	−10 ± 19^b	−10 ± 20^b
HDL-TG^a	−14 ± 29	−24 ± 27^a	−27 ± 26^a	−34 ± 27^ab
TG^a	−3 ± 51	−9 ± 67	−15 ± 56^ab	−20 ± 61^ab
RLP-C	−19 ± 50^a	−16 ± 57^a	−22 ± 56^a	−21 ± 72^a
Apo A-I	−24 ± 20^a	−6 ± 26^b	3 ± 25^b	9 ± 31^bc
Apo A-II	−21 ± 15^a	−14 ± 30^a	−4 ± 19^b	−6 ± 25^b
Apo E	−11 ± 19	−19 ± 28^a	−15 ± 17^a	−16 ± 18^a
CETP activity	−17 ± 19	−27 ± 28^a	−53 ± 48^a	−83 ± 66^ab
LCAT activity	−33 ± 17^a	−22 ± 26^a	−17 ± 33^a	−24 ± 53^a
CETP mass	−31 ± 13^a	−19 ± 19^ab	−13 ± 21	13 ± 29^bcd
LCAT mass	−18 ± 16^a	−13 ± 17^a	−12 ± 20^a	−22 ± 13^a
ApoA-I-containing HDL subpopulations
Preβ-1	−20 ± 46^a	−12 ± 67	−4 ± 57	−1 ± 4^b
Preβ-2	70 ± 224	112 ± 228	12 ± 60	30 ± 70
α-1	−7 ± 43	68 ± 99^b	115 ± 160^ab	177 ± 180^abc
α-2	−23 ± 22^a	−6 ± 26^b	8 ± 31^b	22 ± 42^abc
α-3	−19 ± 32^a	−10 ± 29	−7 ± 28	−10 ± 30
α-4	−20 ± 38^a	−12 ± 36	2 ± 36	4 ± 51
Preα-1	−52 ± 238	159 ± 319	251 ± 416^b	580 ± 920^abc
Preα-2	−6 ± 54	20 ± 81^b	47 ± 63^ab	75 ± 99^abc
Preα-3	−5 ± 48	2 ± 48	9 ± 64	−2 ± 51
Preα-4	−7 ± 45	9 ± 55	5 ± 69	17 ± 58

Letters indicate statistically significant difference from: (a) baseline, (b) 1 month, (c) 3 month, (d) 6 month (two-sided P < 0.05, Tukey's Honestly Significant Difference).

Differences were determined from analyses of log-transformed data.