TABLE 1.
Oxylipin Parent FA | Pre P-OM3 | Post P-OM3 | Fold Change | P |
---|---|---|---|---|
LA | 34.2 (32, 36) | 33.5 (32, 35) | – | >0.05 |
aLA | 0.558 (0.48, 0.65) | 0.551 (0.47, 0.64) | – | >0.05 |
dgLA | 0.204 (0.19, 0.22) | 0.174 (0.16, 0.19) | 0.85 | 0.015 |
AA | 7.24 (6.8, 7.8) | 6.34 (5.9, 6.8) | 0.88 | 0.012 |
EPA | 0.425 (0.31, 0.59) | 3.6 (2.6, 5) | 8.46 | 0.0004 |
DHA | 1.47 (1.2, 1.8) | 3.97 (3.3, 4.8) | 2.71 | 0.0001 |
Before and after 4 weeks of treatment with prescription omega-3 acid ethyl esters (P-OM3) in healthy volunteers (n = 10). Abbreviations: AA, arachidonic acid; aLA, α-linolenic acid; dgLA, dihommo-γ-linolenic acid; DHA, docosahexaenoic acid; EPA, eicosapentaenoic acid; FA, fatty acid; LA, linolenic acid; P-OM3, prescription omega-3 ethyl esters.