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. 2010 Aug;51(8):2074–2081. doi: 10.1194/jlr.M900193-JLR200

TABLE 1.

Plasma content (% of total FA) of the oxylipin parent FA

Oxylipin Parent FA Pre P-OM3 Post P-OM3 Fold Change P
LA 34.2 (32, 36) 33.5 (32, 35) >0.05
aLA 0.558 (0.48, 0.65) 0.551 (0.47, 0.64) >0.05
dgLA 0.204 (0.19, 0.22) 0.174 (0.16, 0.19) 0.85 0.015
AA 7.24 (6.8, 7.8) 6.34 (5.9, 6.8) 0.88 0.012
EPA 0.425 (0.31, 0.59) 3.6 (2.6, 5) 8.46 0.0004
DHA 1.47 (1.2, 1.8) 3.97 (3.3, 4.8) 2.71 0.0001

Before and after 4 weeks of treatment with prescription omega-3 acid ethyl esters (P-OM3) in healthy volunteers (n = 10). Abbreviations: AA, arachidonic acid; aLA, α-linolenic acid; dgLA, dihommo-γ-linolenic acid; DHA, docosahexaenoic acid; EPA, eicosapentaenoic acid; FA, fatty acid; LA, linolenic acid; P-OM3, prescription omega-3 ethyl esters.