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. Author manuscript; available in PMC: 2011 Sep 1.
Published in final edited form as: Behav Brain Res. 2010 Apr 8;212(1):115–120. doi: 10.1016/j.bbr.2010.03.037

Table 2.

Effect and sample sizes of APPSWE and APPWT B6/SJL mice tested in the Morris water maze.

Age Probe Males and Females Combined
APPSWE vs. Tg Neg
 Males and Females Combined
APPSWE vs. APPWT
 Males and Females Combined
APPWT vs. Tg Neg
Mean
Difference1 		Pooled
Standard
Deviation		 Effect
Size		 N Needed
per Group		 Mean
Difference1 		Pooled
Standard
Deviation		 Effect Size N Needed
per Group		 Mean
Difference2 		Pooled
Standard
Deviation		 Effect Size N Needed
per Group
4–5 Months Probe 1 −3.57 12.79 0.28 203 −2.27 13.16 0.17 528 −1.30 11.11 0.12 1146
Probe 2 −2.00 12.87 0.16 650 0.22 12.89 0.02 53885 −2.22 11.41 0.20 416
Probe 3 −3.81 14.11 0.27 216 −4.51 13.70 0.33 146 0.70 14.06 0.05 6330
Mean Probe −3.13 10.01 0.31 162 −2.19 10.33 0.21 350 −0.94 8.71 0.11 1347
6–11 Months Probe 1 2.68 11.16 0.24 273 9.03 11.95 0.76 29 −6.35 11.14 0.57 50
Probe 2 1.49 13.70 0.11 1326 8.49 15.02 0.57 51 −7.00 12.49 0.56 51
Probe 3 4.51 13.77 0.33 148 8.60 15.96 0.54 55 −4.09 12.78 0.32 155
Mean Probe 2.90 9.32 0.31 163 8.71 10.18 0.86 23 −5.81 8.19 0.71 33
12–18 Months Probe 1 6.18 13.70 0.45 79 6.78 12.36 0.55 54 −0.60 14.66 0.04 9368
Probe 2 7.99 13.26 0.60 45 8.38 13.93 0.60 45 −0.39 13.46 0.03 18695
Probe 3 5.70 13.86 0.41 94 7.31 14.07 0.52 60 −1.61 15.10 0.11 1380
Mean Probe 5.40 10.28 0.53 58 7.49 9.84 0.76 29 −2.09 11.18 0.19 450
20–24 Months Probe 1 −0.08 11.32 0.01 314300 7.53 12.79 0.59 47 −7.61 11.27 0.68 36
Probe 2 4.21 11.98 0.35 128 9.68 13.84 0.70 34 −5.47 11.09 0.49 66
Probe 3 14.03 11.84 1.19 13 19.11 11.74 1.63 8 −5.08 13.03 0.39 105
Mean Probe 6.05 8.85 0.68 35 12.11 9.24 1.31 11 −6.06 8.91 0.68 35
1

A negative value indicates a higher mean for APP SWE (Tg2576)

2

A negative value indicates a higher mean for APP WT (Tg5469)