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. Author manuscript; available in PMC: 2010 Jul 14.
Published in final edited form as: Transplant Proc. 1990 Feb;22(1):21–22.

Table 1.

Biochemical Profile Before, During, and After Administration of a Loading Dose of FK 506 (0.15 mg · kg−1)

Before
FK 506
FK + 15 FK + 60 FK + 120
pH 7.37 ± 0.04 7.39 ± 0.03 7.40 ± 0.05 7.41 ± 0.05*
pCO2 (mmHg) 39 ± 5 38 ± 4 37 ± 3 36 ± 3*
pO2 (mmHg) 270 ± 44 266 ± 39 248 ± 48 231 ± 61*
Base excess (mmol · L−1) −2.6 ± 2.7 −1.9 ± 2.0 −1.6 ± 3.2 −1.5 ± 3.3
Na (mmol · L−1) 137 ± 5 139 ± 4 139 ± 5 139 ± 5
K (mmol · L−1) 3.5 ± 0.5 3.4 ± 0.4 3.5 ± 0.4 3.5 ± 0.4
Ca++ (mmol · L−1) 1.07 ± 0.11 1.04 ± 0.11 1.00 ± 0.09 1.00 ± 0.10
Glucose (mg · dl−1) 204 ± 47 210 ± 60 229 ± 73 226 ± 63
Lactate (mmol · L−1) 5.8 ± 2.4 5.6 ± 2.5 5.0 ± 2.6 5.1 ± 2.7

Note: Values are mean ± SD.

*

P < 0.05 compared with baseline values.