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. Author manuscript; available in PMC: 2010 Jul 14.
Published in final edited form as: Islets. 2009 Nov;1(3):273–275. doi: 10.4161/isl.1.3.9781

Figure 1. E2 prevents β-cell apoptosis independently of gene transcription and de novo protein synthesis.

Figure 1

Percentage of apoptotic MIN6 cells treated with Cycloheximide or Actinomycin D. Apoptosis was measured by nuclear morphology as described (3). V: vehicle. # P<0.001, * P<0.05, ** P<0.01