Table 4.
CC50 (μM) values of the perylenequinone against cancer cell lines.
cmpd | NCI-H460 | PC3 | SK-MEL-5 | SN12C | U251 | A2780 | MCF7 | JHU-012 Head&Neck | ||
---|---|---|---|---|---|---|---|---|---|---|
Lung | Prostate | Skin | Colon | Brain | Ovary | Breast | Light | Darkb | Photo-potentiation | |
(+)-2 | 0.52 | 0.71 | 0.86 | 0.66 | 0.49 | 0.28 | 1.1 | 0.81 | 2.8 | 3.5 |
3 | 0.13 | 0.26 | 0.15 | 0.17 | 0.15 | 0.12 | 0.20 | 0.16 | 0.78 | 4.9 |
ent-4 | 0.49 | 0.51 | 0.57 | 1.0 | 0.57 | 0.41 | 0.84 | 1.0 | 1.9 | 1.9 |
16 | 0.51 | 0.71 | 0.55 | 0.58 | 0.50 | 0.22 | 0.84 | 0.23 | 1.3 | 5.8 |
All assays conducted with a 30 min exposure to a 32 W light at 5 cm.
Assays conducted without 30 min light exposure.