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. Author manuscript; available in PMC: 2010 Jul 14.
Published in final edited form as: Transplant Proc. 1990 Feb;22(1):52–56.

Table 2.

Pharmacokinetic Properties of FK 506

Absorption
 Rate: Rapid
 Extent: 27%
Distribution
 Extensive tissue distribution
Elimination
 High-clearance drug
 Completely metabolized
 Less than 1% of the dose excreted in urine
 Half-life: 8.7 hours
Drug interactions
 FK 506 increases CyA concentration
 Potential for inhibition of metabolism of other drugs