Table 2.
Pharmacokinetic Properties of FK 506
Absorption |
Rate: Rapid |
Extent: 27% |
Distribution |
Extensive tissue distribution |
Elimination |
High-clearance drug |
Completely metabolized |
Less than 1% of the dose excreted in urine |
Half-life: 8.7 hours |
Drug interactions |
FK 506 increases CyA concentration |
Potential for inhibition of metabolism of other drugs |