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. 2010 May 19;24(7):1478–1497. doi: 10.1210/me.2010-0029

Figure 9.

Figure 9

HIPK3 maintains Runx2 protein accumulation and OC gene expression. A, HIPK3 knock-down by an ASO directed toward HIPK3 recapitulates the effects of DMAT on Runx2 protein accumulation. B, As compared with the sense strand control oligo, HIPK3 ASO also significantly reduces endogenous OC gene expression in cells transfected with CMV-Runx2. The Col1A1 gene was not affected by HIPK3 ASO. ***, P < 0.001 vs. vehicle.