Table 1.
Serum chemistry analyses of WT and ATF3 KO mice fed HFD
| HFD
|
Reference range
|
||||
|---|---|---|---|---|---|
| ATF3 +/+ | ATF3−/− | P value | Max/min | Citation | |
| Glucose (mg/dl) | 178 ± 8.4 | 168 ± 9.5 | 0.51 | 136/47 | 55, 56 |
| (mmol/liter) | 9.9 ± 0.5 | 9.3 ± 0.5 | 16.3/2.6 | ||
| NEFA (mEq/liter) | 1.8 ± 0.15 | 1.7 ± 0.06 | 0.52 | 1.08/0.96 | 57, 58 |
| (mmol/liter) | 1.8 ± 0.15 | 1.7 ± 0.06 | 1.08/0.96 | ||
| Cholesterol (mg/dl) | 242 ± 17.3 | 272 ± 13.6 | 0.25 | 121/55 | 55, 56 |
| (mmol/liter) | 6.2 ± 0.4 | 6.9 ± 0.3 | 3.1/1.4 | ||
| Triglycerides (mg/dl) | 148 ± 13.0 | 119 ± 1.2 | 0.07 | 169/35 | 55, 56 |
| (mmol/liter) | 1.6 ± 0.1 | 1.3 ± 0.01 | 1.9/0.4 | ||
| Insulin (ng/ml) | 5.4 ± 0.2 | 3.0 ± 0.4 | 0.03 | 1.3/0.7 | 58 and Fig. of this report |
| (pmol/liter) | 929 ± 34 | 516 ± 72 | 224/120 | ||
Fasting sera collected from mice after 12 wk on HFD were analyzed (n = 6–8 mice per group). Data are expressed as means ± sem. References ranges are from fasted mice as reported in the indicated citations. NEFA, Nonesterified fatty acid.