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Cyclic estradiol replacement increases the anorectic effect of apo A-IV in OVX rats. Food intake was measured at 45 min after i4vt administration of apo A-IV (0.5 or 1 μg). Data are the mean ± sem (n = 8 rats/group). *, P < 0.05, **, P < 0.01, compared with saline controls; #, P < 0.05, compared with the oil-treated OVX rats receiving i4vt 0.5 μg of apo A-IV.
