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. Author manuscript; available in PMC: 2010 Jul 14.

Published in final edited form as: Calcif Tissue Int. 2006 Aug 15;79(2):112–117. doi: 10.1007/s00223-006-0074-7

Table 1.

Growth and skeletal parameters at 4, 8, and 12 weeks of age

	Age (weeks)

	4		8		12

Parameter	WT	FHL2 KO	WT	FHL2 KO	WT	FHL2 KO
Body weight (g)
Female	12.82±0.71	11.80±0.55^, ^*	19.28±0.37^**	17.76±0.28^, ^, ^**	22.12±0.50^**	20.90±0.56^**
Male	15.28±0.43	13.17±0.82^*	23.96±0.39	23.23±0.62^*	27.80±0.91	27.25±0.93
Body length (mm)
Female	73.40±2.54	73.33±1.26	85.8±1.20^**	84.83±1.22^**	89.20±1.36^**	89.00±1.29^**
Male	77.60±1.21	73.67±1.52	93.20±0.37	90.83±1.78	95.00±0.63	95.00±1.75
Femur BMC (mg)
Female	6.54±0.49	5.83±0.31^*	16.6±0.93	12.07±0.83^***	19.48±0.22	17.27±0.74^***
Male	7.67±0.42	6.52±0.50^*	15.63±1.01	16.37±1.58	19.27±0.42	20.43±1.57
Femur BMD (mg/cm²)
Female	42.26±1.29	38.90±0.46	63.80±1.74^**	55.53±2.26^, ^*	72.02±1.03	67.12±1.49^***
Male	41.20±2.15	40.17±1.28	65.03±1.95	67.18±4.56	68.72±1.92	77.02±5.24
Tibia BMC (mg)
Female	7.60±0.49	7.50±0.43^*	16.74±1.01	14.07±0.56^***	18.90±0.61	16.88±1.12
Male	10.17±0.48	7.08±0.84^*	16.10±0.28	17.02±1.10	18.85±0.42	19.90±1.06
Tibia BMD (mg/cm²)
Female	34.58±1.13	33.00±1.16	53.00±2.09	47.82±0.95^***	58.10±1.91	54.57±3.11
Male	35.85±1.30	33.28±1.95	51.62±1.94	53.57±2.14	58.38±1.52	60.57±2.82

^*

Significant main effect for treatment at P < 0.05

^**

Significant main effect for gender at P < 0.05

^***

Significant treatment effect for female mice at P < 0.05; n = 5 or 6 in each treatment group (n = 23)