Figure 4.
Predicted SLC16A12 RNA foldings. T-allele and G-allele refer to the SNP rs3740030 (c.-42T/G). Patient has sequences c.-42G and c.-17G. (A–C) RNA foldings for the entire SLC16A12 transcript. Differences in mRNA structure are highlighted (box). The 5′-end is marked (5′). Dotted line: 5′UTR. Arrows: positions c.-42G, c.42U, and c.-17G. (D–F) Predicted RNA foldings for 5′UTR sequences only.