Table 4.
Bivariate Modeling Results
| POAG Related Traits | Genetic Correlation | P | Phenotypic Correlation | P | |
|---|---|---|---|---|---|
| POAG diagnosis | Maximum IOP | 0.801 | 9.6 × 10−6 | 0.552 | 6.0 × 10−21 |
| POAG affected | Maximum VCDR | 0.761 | 4.8 × 10−10 | 0.672 | 1.2 × 10−30 |
| POAG affected | Mean CCT | −0.280 | 0.266 | −0.250 | 0.029 |
| Maximum IOP | Maximum VCDR | 0.445 | 1.2 × 10−3 | 0.292 | 5.5 × 10−11 |
| Maximum IOP | Mean CCT | 0.031 | 0.891 | 0.011 | 0.896 |
| Maximum VCDR | Mean CCT | −0.470 | 2.1 × 10−2 | −0.242 | 3.7 × 10−3 |
Significant correlations are shown in bold; maximum IOP and mean CCT were normalized before bivariate modeling.