Table 5.
Gene | Uninfected (n = 206) |
P‡ | Bacterial Infection (n = 33) |
||||
---|---|---|---|---|---|---|---|
Mean† | 95% CI | Median | Mean† | 95% CI | Median | ||
TNF | 1.58 | 0.82–2.34 | 0.60 | 0.0028 | 2.54 | 1.29–3.80 | 0.77 |
IL1B | 0.77 | 0.32–1.22 | 0.12 | 0.0002 | 0.96 | 0.43–1.49 | 0.34 |
MMP-1 | 2.72 | 1.58–3.86 | 0.41 | 0.0087 | 0.62 | 0.15–1.08 | 0.19 |
MMP-2 | 0.07 | 0.02–0.12 | 0.02 | 0.37 | 0.05 | 0.03–0.06 | 0.04 |
MMP-9 | 0.23 | 0.19–0.27 | 0.15 | <0.0001 | 0.99 | 0.45–1.53 | 0.65 |
TIMP-1 | 15.89 | 12.4–19.4 | 6.81 | 0.084 | 9.11 | 5.53–12.7 | 5.23 |
TIMP-2 | 4.96 | 4.46–5.46 | 3.91 | 0.83 | 5.70 | 3.93–7.47 | 4.88 |
MMP-1/TIMP-1 | 0.10 | 0.10–0.15 | 0.07 | 0.029 | 0.07 | 0.04–0.11 | 0.04 |
Conjunctival gene expression level of the gene of interest is expressed as a ratio to the HPRT-1 expression level in the same sample.
Arithmetic mean of untransformed response.
Interval regression, with P-values adjusted for age, sex, and ethnicity.