Table 7.
Gene | Mandinka (n = 139) |
Wolof (n = 57) |
Fula (n = 18) |
Other (n = 26) |
P‡ | ||||
---|---|---|---|---|---|---|---|---|---|
Mean† | 95% CI | Mean† | 95% CI | Mean† | 95% CI | Mean† | 95% CI | ||
TNF | 2.24 | 1.09–3.39 | 0.65 | 0.39–0.90 | 1.47 | 0.79–2.15 | 1.32 | 0.75–1.90 | <0.0001 |
IL1B | 0.57 | 0.29–1.02 | 0.76 | 0.06–1.45 | 2.41 | 1.88–6.71 | 0.93 | 0.24–2.10 | 0.38 |
MMP-1 | 3.16 | 1.55–4.78 | 0.96 | 0.52–1.45 | 1.43 | 0.17–2.69 | 2.30 | 0.35–4.96 | 0.23 |
MMP-2 | 0.04 | 0.03–0.05 | 0.13 | 0.06–0.32 | 0.05 | 0.03–0.14 | 0.07 | 0.00–0.13 | 0.049 |
MMP-9 | 0.38 | 0.24–0.52 | 0.24 | 0.16–0.32 | 0.33 | 0.12–0.53 | 0.32 | 0.15–0.49 | 0.37 |
TIMP-1 | 17.78 | 14.2–21.4 | 7.51 | 4.80–10.2 | 17.54 | 7.45–42.5 | 13.92 | 2.16–25.7 | <0.0001 |
TIMP-2 | 5.73 | 5.04–6.42 | 3.68 | 2.92–4.43 | 4.40 | 2.50–6.29 | 4.95 | 3.51–6.39 | 0.0001 |
MMP-1/TIMP-1 | 0.11 | 0.09–0.14 | 0.14 | 0.10–0.18 | 0.16 | 0.03–0.28 | 0.10 | 0.05–0.14 | 0.42 |
Conjunctival gene expression level of the gene of interest is expressed as a ratio to the HPRT-1 expression level in the same sample.
Arithmetic mean of untransformed response.
Interval regression, with P-values adjusted for age, sex, and ethnicity.