Table 2.
Neurotransmi-Genes in Amacrine Cells and RGCs
| Gene Symbol | Gene Name | Mean E20 |
Mean P5 |
Mean P11 |
|||
|---|---|---|---|---|---|---|---|
| Amacr | RGCs | Amacr | RGCs | Amacr | RGCs | ||
| Unique expression in RGCs by present call | |||||||
| Chrna7 | Cholinergic receptor, nicotinic, alpha polypeptide 7 | 673 | 918 | 509 | 671 | 869 | 669 |
| Aldh5a1 | Aldehyde dehydrogenase 5 family, member A1 (succinate-semialdehyde dehydrogenase) | 546 | 574 | 709 | 730 | 899 | 473 |
| Unique expression in amacrine cells by Affymetrix “Present”call: | |||||||
| — | — | 9,632 | 1,692 | 20,623 | 957 | 25,627 | 403 |
| — | — | 9,332 | 46 | 16,645 | 113 | 13,509 | 110 |
| Slc1a3 | Solute carrier family 1 (glial high affinity glutamate transporter), member 3 | 6,296 | 199 | 10,550 | 207 | 12,565 | 211 |
| Exoc5 | Exocyst complex component 5 | 5,579 | 419 | 5,683 | 362 | 4,984 | 308 |
| Lin7c | Lin-7 homolog C (C. elegans) | 5,066 | 22 | 3,494 | 24 | 3,118 | 20 |
| Slc32a1 | Solute carrier family 32 (GABA vesicular transporter), member 1 | 4,660 | 1,586 | 14,460 | 1,076 | 14,566 | 2,437 |
| Incenp | Inner centromere protein | 1,832 | 1,488 | 1,518 | 1,012 | 679 | 969 |
| Chrna4 | Cholinergic receptor, nicotinic, alpha polypeptide 4 | 1,330 | 2,952 | 1,323 | 3,994 | 1,221 | 3,943 |
| Kcnh2 | Potassium voltage-gated channel, subfamily H (eag-related), member 2 | 1,266 | 1,572 | 1,445 | 1,186 | 2,960 | 1,010 |
| Th | Tyrosine hydroxylase | 1,130 | 1,117 | 2,815 | 1,193 | 2,737 | 857 |
| Rims1 | Regulating synaptic membrane exocytosis 1 | 1,056 | 105 | 1,936 | 63 | 3,922 | 93 |
| Grm2 | Glutarnate receptor, metabotropic 2 | 993 | 570 | 2,480 | 559 | 3,854 | 293 |
| Gabra3 | Gamma-aminobutyric acid (GABA-A) receptor, subunit alpha 3 | 889 | 336 | 1,927 | 455 | 2,468 | 548 |
| Stx3 | Syntaxin 3 | 714 | 107 | 375 | 215 | 1,336 | 167 |
| Rab15 | RAB15, member RAS oncogene family | 707 | 121 | 382 | 221 | 707 | 213 |
| Nedd1 | Neural precursor cell expressed, developmentally down-regulated gene 1 | 671 | 175 | 937 | 84 | 318 | 98 |
| Cacna1a | Calcium channel, voltage-dependent, P/Q type, alpha 1A subunit | 581 | 3,794 | 653 | 2,995 | 1,153 | 3,504 |
| Cln3 | Ceroid lipofuscinosis, neuronal 3, juvenile (Batten, Spielmeyer-Vogt disease) | 506 | 638 | 484 | 1,512 | 668 | 944 |
| Lin7b | Lin-7 homolog b (C. elegans) | 488 | 172 | 620 | 659 | 1,553 | 763 |
| Slc6a9 | Solute carrier family 6 (neurotransmitter transporter, glycine), member 9 | 453 | 984 | 2,036 | 818 | 7,792 | 1,447 |
| Drd4 | Dopamine receptor D4 | 439 | 582 | 273 | 230 | 490 | 425 |
| Htr3a | 5-hydroxytryptamine (serotonin) receptor 3a | 388 | 83 | 304 | 184 | 1,096 | 181 |
| Nos1ap | Nitric oxide synthase 1 (neuronal) adaptor protein | 330 | 1,668 | 296 | 1,216 | 330 | 1,710 |
| Gabrg3 | Gamma-aminobutyric acid (GABA) A receptor, subunit gamma 3 | 230 | 79 | 227 | 123 | 320 | 62 |
| Grin2a | Glutamate receptor, ionotropic, N-methyl D-aspartate 2A | 210 | 107 | 142 | 41 | 192 | 97 |