TABLE 1.
Dietary intake of choline and betaine in women at 45 d postpartum1
Intake | Placebo group (n = 46) | Supplement group (n = 48) |
Dietary choline (mg/d) | 364 ± 18 (139–671)2 | 338 ± 14 (124–622) |
Total choline for diet plus supplement groups (mg/d) | 364 ± 183 | 1088 ± 144 |
Betaine (mg/d) | 295 ± 32 | 263 ± 23 |
Pregnant women at <18 wk gestation were enrolled and randomly assigned to receive either a choline supplement (750 mg choline/d) or a placebo (corn oil). Participants took these supplements from 18 wk pregnancy to 45 d postpartum. Participants kept 3-d food records immediately before the 45-d postpartum study visit. Participants were asked to record all food and beverage intakes on 2 typical weekdays and 1 weekend day. Food records were analyzed with Food Processor SQL nutrient analysis software (version 10.3; ESHA Research, Salem, OR). Daily choline and betaine intakes (mg/d) were estimated for each subject by taking an average of their 3-d intake. Groups were compared by t tests.
Mean concentration ± SE; range of dietary intake of choline (excluding the supplement) in parentheses (all such values).
Mean concentration ± SE (all such values).
Significantly different from placebo group, P < 0.0001.