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. Author manuscript; available in PMC: 2011 Mar 1.
Published in final edited form as: Gene Ther. 2009 Oct 1;17(3):315–327. doi: 10.1038/gt.2009.126

Figure 7. Beclin-1 and H11/HspB8 are upregulated in ΔPK-treated cultures and xenografts.

Figure 7

A2058 cultures were infected with ΔPK (moi = 0.5) and cell extracts obtained at various times p.i. were immunoblotted with antibody to Beclin-1 (a), stripped and re-probed with antibodies to H-11/HspB8 (b) and actin. Duplicates of the A2058 xenografts examined for calpain and caspase activation in Fig. 6, were immunoblotted with antibody to Beclin-1 (c) stripped and re-probed with antibodies to H11/HspB8 (d) and actin. Each lane represents a different tumor. Representatives of three replicate experiments are shown for each antibody. Data were quantified by densitometric scanning as described in Materials and Methods, and results are expressed as densitometric units. (*** p<0.001 vs. Mock)