Table 1.
Abundantly expressed genes of adult type II cells
| Gene Title | Gene Symbol | Abundance (f. u.) | GO Biological Process |
|---|---|---|---|
| Surfactant protein A | SFTPA2 | 16,891 ± 2,365 | respiratory gaseous exchange |
| HECT, UBA, and WWE domain containing 1 | HUWE1 | 14,680 ± 2,262 | protein polyubiquitination |
| Ferritin, heavy polypeptide 1 | FTH1 | 13,898 ± 2,477 | iron ion transport |
| actin, β | ACTB | 12,390 ± 1,735 | |
| Ubiquitin C | UBC | 11,949 ± 1,819 | protein ubiquitination |
| Tumor protein, translationally controlled 1 | TPT1 | 11,844 ± 1,781 | |
| Ferritin, light polypeptide | FTL | 11,613 ± 1,759 | iron ion transport |
| Eukaryotic translation elongation factor 1α1 | EEF1A1 | 11,464 ± 1,548 | protein biosynthesis |
| Surfactant protein C | SFTPC | 11,436 ± 2,858 | respiratory gaseous exchange |
| Secretoglobin, family 1A, member 1 | SCGB1A1 | 10,924 ± 3,753 | signal transduction |
| Surfactant protein B | SFTPB | 10,121 ± 1,694 | respiratory gaseous exchange |
| Spermidine/spermine N1-acetyltransferase | SAT | 10,104 ± 2,218 | |
| Thymosin, beta 4, X-linked | TMSB4X | 10,062 ± 2,125 | cytoskeleton organization and biogenesis |
| S100 calcium binding protein A6 (calcyclin) | S100A6 | 9,665 ± 2,157 | regulation of cell cycle |
| Eukaryotic translation initiation factor 1 | EIF1 | 9,148 ± 1,052 | protein biosynthesis |
| Chemokine (C-X-C motif) ligand 2 | CXCL2 | 9,035 ± 2,525 | chemotaxis |
| b2-microglobulin | B2M | 8,888 ± 1,196 | immune response |
| Actin, γ1 | ACTG1 | 8,861 ± 807 | |
| Peptidylprolyl isomerase A (cyclophilin A) | PPIA | 8,382 ± 807 | protein folding |
| Stratifin | SFN | 8,340 ± 3,369 | regulation of cell cycle |
| Ubiquitin B | UBB | 8,308 ± 1,468 | protein ubiquitination |
| Secretory leukocyte peptidase inhibitor | SLPI | 8,190 ± 1,769 | |
| Interleukin-8 | IL8 | 8,082 ± 1,438 | angiogenesis |
| Annexin A2 | ANXA2 | 7,884 ± 1,185 | skeletal development |
| Heat shock 90 kDa protein 1, α | HSPCA | 7,656 ± 3,418 | response to unfolded protein |
The 25 most abundantly expressed genes, excluding ribosomal proteins, are listed. Data are means ± SE for 5 experiments.