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. 2010 Apr 16;299(1):L36–L50. doi: 10.1152/ajplung.00427.2009

Table 4.

Genes repressed >3-fold by dexamethasone plus cAMP

Gene Title DCI/Control GO Biological Process/Molecular Function
BMP & activin membrane-bound inhibitor 0.17
Likely ortholog of mouse limb-bud and heart gene 0.17
Serpin peptidase inhibitor, clade B (ovalbumin), 2 0.19 Anti-apoptosis
Adhesion molecule with Ig-like domain 2 0.20 Cell adhesion
Solute carrier organic anion transporter family, 2A1 0.20 Lipid transport
Thrombospondin 1 0.21 Cell motility/cell adhesion
Dickkopf homolog 1 (Xenopus laevis) 0.22 Development/Wnt receptor signaling pathway
Potassium channel tetramerisation domain containing 12 0.22 Potassium ion transport
NADPH oxidase 4 0.23 Electron transport
MARCKS-like 1 0.23
Caldesmon 1 0.29 Muscle contraction/development
Protease, serine, 23 0.25 Proteolysis
Ectodermal-neural cortex (with BTB-like domain) 0.26 Development
Sema domain, immunoglobulin domain (semaphorin) 3C 0.26 Immune response/tyrosine kinase signaling
Plasminogen activator, urokinase 0.27 Proteolysis
Collagen, type I, α1 0.27 Skeletal development
Growth arrest and DNA-damage-inducible, α 0.27 Regulation of cyclin dependent protein kinase
Collagen, type IV, α3 (Goodpasture antigen) 0.27 Phosphate transport/apoptosis/signal transduction
Interleukin-32 0.28 Immune response/cell adhesion
Immediate early response 3 0.28 Apoptosis
Protease, serine, 2 (trypsin 2) 0.28 Proteolysis
Cystatin E/M 0.28 Morphogenesis
Laminin, γ2 0.28 Cell adhesion
K intermed/small conductance Ca-activated channel N 4 0.29 Ion transport
Neuregulin 1 0.29 Nervous system development/transcription
Integrin, α2 (CD49B, α2 subunit of VLA-2 receptor) 0.29 Cell adhesion
Transforming growth factor, β2 0.29 Regulation of cell cycle
Integrin, β6 0.30 Cell adhesion/integrin-mediated signaling pathway
Glutathione S-transferase M3 (brain) 0.30 Establishment of blood-nerve barrier
Collagen, type IV, α4 0.30 Phosphate transport
Collagen, type IV, α2 0.31 Phosphate transport
Complement component 5 0.31 Inflammatory response/chemotaxis
Tumor necrosis factor receptor superfamily, member 21 0.31 Apoptosis/signal transduction
Tropomyosin 1α 0.31 Regulation of muscle contraction
Chromosome 2 open reading frame 23 0.32
Cadherin 2, type 1, N-cadherin (neuronal) 0.32 Cell adhesion
Polo-like kinase 2 (Drosophila) 0.33 Protein amino acid phosphorylation
ATPase, Class V, type 10A 0.33 Cation transport
Plasminogen activator, urokinase receptor 0.33 Signal transduction/regulation of proteolysis
S100 calcium binding protein A2 0.33

Data are means of 5 experiments; P < 0.003 for DCI-treated vs. control.