Fig. 1.
Change in aortic diameter over time after thoracic aortic aneurysm (TAA) induction. Aortic diameter was determined at baseline and terminal surgery in each animal using digital micrometry. Aortic diameter values were expressed as percent changes from baseline (100%) in each animal. After TAA induction, aortic diameter was elevated at all time points (*P < 0.001 vs. reference control), and 16-wk values were significantly greater than those at the other time points (#P < 0.05 vs. 2 wk, &P < 0.05 vs. 4 wk, and +P < 0.05 vs. 8 wk).