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A: mean arterial blood pressures (MAP) measured by telemetry in lean Zucker rats (LZRs) and obese Zucker rats (OZRs) with and without hydrochlorothiazide (HCT) treatment. Values are 3-day averages. B: frequency of elevated systolic blood pressure during the final week of the study. Values are means ± SE. *P < 0.05 vs. LZRs, HCT-treated LZRs (LZR + HCT), and HCT-treated OZRs (OZR + HCT); †P < 0.05 vs. treatment-matched LZRs; ‡P < 0.05 vs. strain-matched untreated rats.
