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Concentration-response curves for 5′-N-ethylcarboxamidoadenosine (NECA)-mediated aortic relaxation/contraction in A1 adenosine receptor (A1AR) wild-type (A1WT; A) and A1AR knockout (A1KO; B) with control (CON), allergic (SEN), and adenosine aerosolized allergic (SEN + AD) groups. Values are expressed as means ± SE; n = 10 mice. On y-axis, positive and negative values indicate relaxation and contraction, respectively. *P < 0.05 compared with A1WT CON; #P < 0.05 compared with A1WT SEN.
