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Effects of nanoinjections of Bic into the VLM on BAT thermogenesis elicited by pontomedullary transection (Ponto-Med TranX). Ponto-Med TranX (L and R) evoked an increase in BAT SNA (peak: +1,318% of intact control), BAT Temp, Exp CO2, HR, and MAP. Bilateral nanoinjections of Bic into the VLM reversed the increases in BAT SNA (to 109% of pretransection control), BAT Temp, Exp CO2, and HR and increased MAP.
