Table 2.
Stromatoxin-1 (100 nM) does not significantly change any of the UBSM contraction parameters under conditions of UBSM membrane depolarization induced by 20 mM KCl or 1 μM carbachol
| N | n | Amplitude | Force | Frequency | Duration (half-width) | Tone | P Value | |
|---|---|---|---|---|---|---|---|---|
| 20 mM K+-induced contractions | 7 | 9 | 101.23 ± 8.15 | 101.28 ± 8.74 | 101.84 ± 2.46 | 96.83 ± 4.68 | 96.74 ± 2.20 | NS |
| 1 μM carbachol-induced contractions | 7 | 8 | 112.00 ± 7.41 | 113.50 ± 7.02 | 106.19 ± 7.29 | 103.82 ± 1.57 | 91.67 ± 5.67 | NS |
Values are means ± SE in %; N, no. of rats; n, no. of urinary bladder smooth muscle (UBSM) strips. NS, nonsignificant (lack of statistical significance).