Table 1.

Effect of ouabain on blood pressure

	Vehicle	Ouabain (1 μg/kg body wt for 8 days)
MAP. mmHg	75.93 ± 4.13	94.93 ± 2.66*
SBP, mmHg	92.27 ± 10.03	113.3 ± 2.598*
DBP, mmHg	65.23 ± 3.56	86.1 ± 2.82*
Heart rate, beats/min	257.1 ± 20.13	253.5 ± 3.5

Values are means ± SE. MAP, mean arterial pressure; SBP and DBP, systolic and diastolic blood pressure, respectively. Sprague-Dawley rats were treated intraperitoneally for 8 days with ouabain (1 μg/kg body wt). After 8 days, blood pressure was determined by inserting a PE catheter in ketamine-anesthetized rats as described in experimental procedures.

^*P < 0.05 by Student's t-test.