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. 2010 Jan 28;109(1):252–261. doi: 10.1152/japplphysiol.01291.2009

Table 3.

Genes associated with the ubiquitin-mediated proteolysis pathway that were altered by exercise

Gene Name Gene Symbol Fold Change
f-box and wd-40 domain protein 7 (archipelago homolog, Drosophila) FBXW7 0.5
Ubiquitin-conjugating enzyme e2, j1 (ubc6 homolog, yeast) UBE2J1 0.6
Ubiquitin-conjugating enzyme e2b (rad6 homolog) UBE2B 0.7
Cullin 4a CUL4A 1.3
Ubiquitin-conjugating enzyme e2l 3 UBE2L3 1.4
f-box and wd-40 domain protein 11 FBXW11 1.4
Tripartite motif-containing 37 TRIM37 1.4
Ubiquitin protein ligase e3a (human papilloma virus e6-associated protein, Angelman syndrome) UBE3A 1.6
Suppressor of cytokine signaling 1 SOCS1 1.6

Fold change is defined as the geometric mean of expression levels of After/Before. A fold change of 0.6 indicates the expression level after exercise is 60% of the expression level before the exercise. A fold change of 1.3 indicates the expression level after the exercise is 130% of the expression level before the exercise.