Table 4.
Genes in the Jak-STAT signaling pathway that were altered by exercise
| Gene Name | Gene Symbol | Fold Change |
|---|---|---|
| Interleukin 2 receptor, beta | IL2RB | 2.2 |
| Signal transducer and activator of transcription 1, 91 kDa | STAT1 | 0.6 |
| Cyclin d2 | CCND2 | 1.8 |
| Interferon (alpha, beta and omega) receptor 2 | IFNAR2 | 1.3 |
| Signal transducer and activator of transcription 4 | STAT4 | 2.6 |
| Suppressor of cytokine signaling 2 | SOCS2 | 2 |
| Phosphoinositide-3-kinase, regulatory subunit 1 (p85 alpha) | PIK3R1 | 1.7 |
| Interleukin 10 receptor, alpha | IL10RA | 1.6 |
| Suppressor of cytokine signaling 1 | SOCS1 | 1.6 |
Fold change is defined as the geometric mean of expression levels of After/Before. A fold change of 0.6 indicates the expression level after exercise is 60% of the expression level before the exercise. A fold change of 1.3 indicates the expression level after the exercise is 130% of the expression level before the exercise.