Table 4.
Linear and multivariate analysis of relationship between SGRQ score and sputum neutrophil percentage at the baseline visit.
| Linear Regression | Multiple Regression | ||||||
|---|---|---|---|---|---|---|---|
| Independent Variables in Model | Estimate(SE) | p-value | R-square | Estimate(SE) | p-value | R-square | |
| Age | -0.453 (0.148) | 0.002 | 0.026 | -0.471 (0.147) | 0.001 | 0.179 | |
| BMI | 0.387 (0.176) | 0.028 | 0.014 | 0.428 (0.174) | 0.014 | ||
| Concomitant ICS use | -6.813 (2.333) | 0.004 | 0.024 | -2.666 (2.293) | 0.246 | ||
| Current smoking status | -1.941 (2.077) | 0.351 | 0.003 | -1.062 (2.089) | 0.611 | ||
| Pack years | 0.051 (0.036) | 0.163 | 0.006 | 0.086 (0.035) | 0.014 | ||
| Number of prior exacerbations | 2.973 (0.649) | <0.001 | 0.057 | 1.923 (0.651) | 0.003 | ||
| FEV1 % predicted | -0.328 (0.065) | <0.001 | 0.069 | -0.307 (0.068) | <0.001 | ||
| Gender | 1.571 (2.115) | 0.458 | 0.002 | 4.083 (2.121) | 0.055 | ||
| Sputum neutrophil % | 0.113 (0.063) | 0.077 | 0.009 | 0.130 (0.061) | 0.035 | ||
Other independent variables were included in this analysis as shown. Post-bronchodilator FEV1 was used.