Table 5.
Linear and multivariate analysis of relationship between SGRQ score and sputum neutrophil percentage at year 1.
| Linear Regression | Multiple Regression | ||||||
|---|---|---|---|---|---|---|---|
| Independent Variables in Model | Estimate(SE) | p-value | R-square | Estimate(SE) | p-value | R-square | |
| Age | -0.174 (0.185) | 0.348 | 0.003 | -0.282 (0.175) | 0.108 | 0.208 | |
| BMI | 0.244 (0.213) | 0.252 | 0.004 | 0.391 (0.207) | 0.060 | ||
| Concomitant ICS use | -9.516 (2.814) | <0.001 | 0.038 | -3.751 (2.803) | 0.182 | ||
| Current smoking status | -3.060 (2.454) | 0.214 | 0.005 | -1.049 (2.403) | 0.663 | ||
| Number of exacerbations during year 1 | 3.936 (0.666) | <0.001 | 0.107 | 3.230 (0.683) | <0.001 | ||
| Pack years | 0.146 (0.042) | <0.001 | 0.039 | 0.157 (0.040) | <0.001 | ||
| FEV1 % predicted | -0.320 (0.076) | <0.001 | 0.057 | -0.190 (0.081) | 0.020 | ||
| Gender | 0.633 (2.565) | 0.805 | 0.000 | 3.038 (2.490) | 0.223 | ||
| Sputum neutrophil % | 0.205 (0.080) | 0.011 | 0.022 | 0.138 (0.078) | 0.079 | ||
Other independent variables were included in this analysis as shown. Post-bronchodilator FEV1 was used.