Table 4.
Summary of outcomes reported in the included studies
| Variable | No. of studies with available information | Median (range) |
|---|---|---|
| Intrahepatic recurrences rate after Initial Hx (%) | 215, 9, 10, 12-15, 17, 21-27, 29-34 | 55.2 (34.6-78) |
| Median/mean recurrent intervals (months) after initial Hx | 155, 8, 10, 13-16, 18, 22, 27, 28, 30-33 | 22.4 (6-33.3) |
| Resectability rate (%) | 235, 9, 10, 12-17, 20-27, 29-34 | 22.8 (8.7-44) |
| No. of repeat Hx | 295, 9-35 | 1149* |
| Mean age (years) | 178, 10, 11, 13-17, 20, 22, 26, 28, 30-32, 34, 35 | 59.5 (45-66.9) |
| Male (%) | 198, 10, 11, 13-19, 22, 26, 28, 30-32, 34, 35 | 81.2 (68-91.6) |
| Liver cirrhosis (%) | 158-11, 14-17, 19, 20, 22, 26, 28, 30, 31 | 68.6 (36-100) |
| Solitary recurrent HCC (%) | 198, 9, 13-20, 22, 24, 26, 28, 30-32,34, 35 | 64.2 (37.5-83.3) |
| Maxium tumor size <3 cm (%) | 88, 9, 14, 15, 19, 26, 31, 35 | 63.6 (27-76.1) |
| Minor resection (%) | 188-18, 22, 26, 30- 32, 34 | 95.5 (71.4-100) |
| Median/mean operating time (min) | 913, 15, 16, 19, 22, 26, 30, 32, 34 | 267(136-365) |
| Median/mean blood loss (mL) | 1313-16, 19, 22, 26, 28-30, 32, 34, 35 | 603 (211-1980) |
| Morbidity (%) | 1210, 13, 15, 16, 18, 22, 28-32, 35 | 23.5 (6.2-68.2) |
| Mortality (%) | 245, 8-10, 12-23, 26, 28-32, 34, 35 | 0 (0-8.0) |
| Overall survival after recurrence | ||
| Median time (months) | 88, 10, 14, 15, 18, 22, 28, 33 | 27.1 (21-61.5) |
| 1-year (%) | 255, 8-22, 25-31,34, 35 | 91.0(69-100) |
| 3-year (%) | 265, 8-24, 26-31, 34, 35 | 63.4 (21.0-87.0) |
| 5-year (%) | 225, 9, 11-14, 16, 17, 19, 21, 23, 24, 26-35 | 48.5(25.0-87.0) |
Hx: hepatectomy. HCC: hepatocellular carcinoma. * total