Table 3.
Endoscopic findings at baseline, n (%)
| Children < 20 kg | Children ≥20 kg | ||||
|---|---|---|---|---|---|
| Category | Esomeprazole 5 mg (0.3-0.6 mg/kg) (n = 26) |
Esomeprazole 10 mg (0.6-1.0 mg/kg) (n = 23) |
Esomeprazole 10 mg (0.2-0.5 mg/kg) (n = 31) |
Esomeprazole 20 mg (0.3-1.0 mg/kg) (n = 29) |
Total (N = 109) |
| Other reflux esophagitis | 14 (54) | 11 (48) | 15 (48) | 16 (55) | 56 (52) |
| Erosive esophagitis | 12 (46) | 12 (52) | 16 (52) | 13 (45) | 53 (49) |
| LA grade A | 6 (23) | 6 (26) | 11 (36) | 9 (31) | 32 (29) |
| LA grade B | 6 (23) | 5 (22) | 5 (16) | 3 (10) | 19 (17) |
| LA grade C | 0 | 1 (4) | 0 | 0 | 1 (1) |
| LA grade D | 0 | 0 | 0 | 1 (3) | 1 (1) |
| Hiatal hernia | 4 (15) | 3 (13) | 8 (26) | 4 (14) | 19 (17) |
| Other abnormality* | 11 (42) | 10 (44) | 16 (52) | 18 (62) | 55 (50) |
*Abnormalities occurring in ≥4 patients were nodularity (n = 20 [18%]), erythema/hyperemia (n = 23 [21%]), edema (n = 11 [10%]), prominent esophageal folds (n = 11 [10%]), and friability (n = 4 [4%]).
LA: Los Angeles.