. Author manuscript; available in PMC: 2011 Jul 1.

Published in final edited form as: J Allergy Clin Immunol. 2010 Jul;126(1):160–165.e3. doi: 10.1016/j.jaci.2010.04.037

Table II.

Replication of TSLP SNP association with EE in two independent case-control cohorts

	Discovery Cohort¹				Replication Cohort²

SNP	MAF Cases	MAF Controls	OR	P-value	MAF Cases	MAF Controls	OR	P-value	Combined P-value³
rs3806933	0.31	0.40	0.66	2.38E-03	0.31	0.41	0.66	6.10E-02	1.43E-03
rs2289276	0.24	0.26	0.86	3.43E-01	0.26	0.23	1.17	5.01E-01	4.74E-01
rs10062929	0.08	0.15	0.45	5.79E-04	0.09	0.19	0.36	3.31E-04	3.16E-06
rs2289277	0.31	0.41	0.64	1.35E-03	0.36	0.43	0.75	1.69E-01	2.14E-03
rs11466749	0.11	0.17	0.52	3.08E-03	0.11	0.21	0.46	5.00E-03	1.86E-04
rs11466750	0.09	0.15	0.70	9.02E-03	0.10	0.19	0.46	9.00E-03	8.48E-04

The discovery cohort was composed of 170 EE cases and 466 allergic and non-allergic controls as described in Table I

The replication cohort was composed of either 87 EE cases and 114 allergic and non-allergic controls or 87 EE cases and 122 allergic and non-allergic controls for SNP rs10062929

Combined P-values from the discovery and replication cohorts using Fisher’s method