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Sporozoite titration for subcutaneous challenge
| C57BL/6a) | BALB/c | ICR (CD-1) | |||
|---|---|---|---|---|---|
| SPZ | % infected | SPZ | % infected | SPZ | % infected |
| 30 | 60% | 1,000 | 0% | 1,000 | 0% |
| 100 | 100% | 2,000 | 0% | 3,000 | 0% |
| 300 | 100% | 3,000 | 60% | 5,000 | 0% |
| 4,000 | 90% | 10,000 | 80% | ||
| 5,000 | 90% | 15,000 | 100% | ||
| 8,000 | 80% | 20,000 | 0% | ||
| 10,000 | 0% | ||||
a) N = 5/group for C57BL/6 and ICR (CD-1), N=10/group for BALB/c. Shown is one representative titration experiment. Results were confirmed in independent repeat experiments.
