. Author manuscript; available in PMC: 2011 Jul 1.

Published in final edited form as: Eur J Cancer. 2010 Jun 4;46(11):2045–2051. doi: 10.1016/j.ejca.2010.05.007

Table 4.

Grade 1 or Greater Rash and Diarrhoea by EGFR Polymorphism

Polymorphism	Genotype	n	Rash %	p-value	Diarrhoea %	p-value
Intron 1 CA(n)	Short (≤35)	62	48.1	NS	36.3	NS
	Long (>35)	47	61.8	NS	48.1	NS

216G>T	G/G	51	52.9		27.5
	T/G	41	46.3	0.01^/0.003^*	58.5	0.01^/0.004^**
	T/T	16	87.5		43.8

191C>A	C/C	74	59.5		40.5
	A/C	22	50	NS	31.8	NS
	A/A	2	0		50

Arg497Lys	Arg/Arg	62	48.3		41.9
	Lys/Arg	39	66.7	0.07^***	41	NS
	Lys/Lys	5	60		20

codominant model

^**

recessive model

^***

dominant model