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Chronic morphine administration does not increase behavioral hypersensitivity following L5 nerve transection surgery. (a) Thermal hyperalgesia measurement of acute analgesia and tolerance to continuous subcutaneous morphine administration. Thermal hyperalgesia (b) and mechanical allodynia (c) were measured in saline, morphine 7d and morphine 14d treatment groups following L5 nerve transection surgery on day 7. **p<0.01, ***p<0.001 compared to saline.
