Table 2.
Clinical course of Adenovirus infections.
| Clinical Presentation | Diagnosis of Adenovirus | Therapy for Adenovirus | Viral Outcome (copies/ml) | Current Status | |
|---|---|---|---|---|---|
| 1 | Hepatitis Day +98 |
Autopsy | None | Death | Death Day +101 |
| 2 | Pulmonary Day +180 |
Serum* and BAL PCR | Cidofovir 1mg/kg QOD ×7 doses IVIG ×1 dose |
45,000→ 2,000→ negative | ECOG 4 Day +392 |
| 3 | Pulmonary Day +64 |
Serum* PCR | Cidofovir 4mg/kg qweek ×3 doses |
560,000→ 25,700→ death prior to repeat | Death Day +92 |
| 4 | Cystitis Day +168 |
Serum, CSF, Urine* PCR | Cidofovir 1mg/kg QOD ×3 doses IVIG ×2 doses |
2 mill→ 15 mill → 800→ no repeat | ECOG 1 Day +434 |
| 5 | Cystitis Day +218 |
Urine*, and Serum PCR | Cidofovir 1mg/kg QOD ×7 doses |
370,000→ 1,000→ no repeat | Death Day +1020 |
| 6 | Pulmonary Day +30 |
Serum*, BAL, and Stool PCR | Cidofovir 1mg/kg QOD ×5 doses IVIG ×3 |
18,000→ death prior to repeat | Death Day +46 |
*used to determine viral outcome.