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Levels of KC (murine CXCL1) in mouse serum (left axis) and mouse whole thigh homogenate (right axis) 24 h after infection with S. pyogenes. KC was measured by ELISA. Infection with parent strain H292 reduced chemokine levels compared with those mice infected with mutant strain H575 in both serum and thigh muscle. n = 10 mice per group.
