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. Author manuscript; available in PMC: 2010 Jul 15.
Published in final edited form as: Endocrinology. 2006 Aug 31;147(12):5653–5661. doi: 10.1210/en.2006-1055

Fig. 5.

Fig. 5

Effect of osteoblast-specific PAPP-A overexpression in transgenic mice on postnatal growth. Body weights of F1 and F2 generation mice derived from founder 26 were determined at different ages. The body weight of PAPP-A transgenic mice was significantly higher than that of the wild-type littermates at 5 wk of age (P < 0.05; n = 3). No significant difference in body weight between transgenic mice and wild-type littermates was noticed at an age of 3 or 6 months (P > 0.05).