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Matrix metalloproteinase (Mmp) 3 and Mmp-12 proteins increase with aging in a depot-dependent manner. Lysates of undifferentiated perirenal and epididymal preadipocytes cultured from young (3 months), middle-aged (17 months), and old (30 months) rats were analyzed by Western blotting for Mmp3 (A) and Mmp12 (B). *p < .05 by analysis of variance; N = 7.
