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. 2010 Mar 3;87(3):524–534. doi: 10.1093/cvr/cvq068

Figure 4.

Figure 4

Reduced expression of p53 in p53−/−/myo+/+ mice is correlated with myotrophin expression. (A) Immunoblot analysis of p53 showing downregulation of p53 in p53−/−/myo+/+ mice compared with myo-Tg mice; (B) Semi-quantitative RT-PCR analysis showing downregulation of myo transcript in p53−/−/myo+/+ mice compared with myo-Tg mice; (C) Immunoblot analysis of myo protein showing reduced expression of myo in the absence of p53 in p53−/−/myo+/+ mice compared with myo-Tg mice. (GAPDH was analysed as a loading control).