Figure 1.

Multiple alignments of partial gyrA, gyrB and parE fragments in Salmonella Typhi and Salmonella Paratyphi A. Wild-type alleles for each gene are indicated by a plus symbol (+). The mutations tested in this paper are shown in black squares and the wild-type amino acid is indicated on top of the alignments for codons containing target mutations. The amino acids for mutations are shown in brackets after the allele names. (a) Alignment of gyrA showing polymorphisms in codons 83 and 87, of which two are triallelic polymorphisms (Trips). (b) Alignment of gyrB with three mutations. Two silent mutations in Salmonella Paratyphi A are shown in grey squares. (c) Alignment of parE with two mutations.