FIGURE 5.
Oxidative stress in the LV of DS rats in the 5 experimental groups at 19 weeks of age. A, Representative dihydroethidium staining for superoxide production in LV sections. Scar bar: 100 μm. B, NADPH oxidase–dependent production in LV homogenates prepared from rats of the (1) control, (2) HF, (3) HYD, (4) OLM + AZE, and (5) APO groups. Data are expressed as relative light units (RLU) per milligram of protein and are means ± SEM for 6 rats of each group. *P < 0.05 versus control group; †P < 0.05 versus HF group. C, The GSH:GSSG ratio in LV tissue. Data are means ± SEM for 6 rats of each group.