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. 2010 Jul 15;5(7):e11607. doi: 10.1371/journal.pone.0011607

Figure 6. DCB-3503 inhibited the elongation step of translation.

Figure 6

A. DCB-3503 treatment induced accumulation of polysomes in HepG2 and HeLa cells after 1-hour treatment. B. DCB-3503 induced accumulation of mRNAs of cyclin D1 and β-Actin in polysomal fractions in the sucrose gradient in HepG2 cells. A and B were representatives from three separate experiments with similar results.