Table 5.

Comparative efficacy of therapeutic interventions for reducing A1C levels

Strategy/Drug	Expected Reduction in A1C (%)
Weight reduction and increase in physical activity	1.0 - 2.0
Metformin	1.0 - 2.0
Insulin as additional therapy	1.5 - 3.5
Sulfonylurea	1.0 - 2.0
Glitazones	0.5 - 1.4
GLP1 Agonists	0.5 - 1.0
DPP-4 Inhibitors	0.5 - 0.8
Alpha-glycosidase Inhibitors	0.5 - 0.8
Glinides	0.5 - 1.5