Figure 4. CHD7 sites bound and not bound by P300 can activate transcription.

(A) Comparison of 1000 randomly selected P300 sites to 1000 randomly selected CHD7 sites. (B) Enhancer assay. OCT4 sites correspond to MTLs that were previously shown to activate the luciferase reporter gene and serve as positive controls. MYC sites correspond to Myc MTLs that fail to activate the luciferase reporter gene and serve as negative controls. -, untransfected.