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. Author manuscript; available in PMC: 2011 Jul 7.
Published in final edited form as: J Am Chem Soc. 2010 Jul 7;132(26):8973–8983. doi: 10.1021/ja1007867

Figure 5. Inhibition of aggregation is specific for cations that bind imidazole.

Figure 5

100 μM NaCl, NH4Cl,MgCl2, CaCl2, or ZnCl2 was added to 7.5 μM hIAPP in 100 mM Tris, 100 mM NaCl, pH 7.5 buffer and amyloid formation was followed by changes in the fluorescence of the amyloid specific dye Thioflavin T (25 μM). Samples were shaken at 60 Hz. Traces are averages for n= 8 experiments.