Figure 2.

AMPAR-mediated mEPSC amplitude, but not conductance was increased in 1-day FZP-withdrawn rats. mEPSC amplitude was increased in 1-day FZP-withdrawn rats without an effect on mEPSC frequency, rise time or decay kinetics, or RMP. (a) Representative plot of the results of non-stationary noise analysis (NSNA) of mEPSCs showed an increase in current amplitude, but no change in slope conductance in an FZP-withdrawn (open circles/dotted line) vs a CON (close circles/solid line) neuron. (b) Mean mEPSC conductance in CA1 neurons from CON (closed bars, n=6) and 1-day FZP-withdrawn (open bars, n=7) rats indicated no significant difference in AMPAR conductance between experimental groups at this time point.